Consequences of a multi-generation exposure to uranium on Caenorhabditis elegans life parameters and sensitivity.

Benoit Goussen 1, 2, * Florian Parisot 1 Rémy Beaudouin 2 Morgan Dutilleul 1 Adeline Buisset-Goussen 1 Alexandre R R Péry 2 Jean-Marc Bonzom 1
* Corresponding author
1 PRP-ENV/SERIS/LECO - Laboratoire d'écotoxicologie des radionucléides
2 INERIS - Institut National de l'Environnement Industriel et des Risques
Abstract : The assessment of toxic effects at biologically and ecologically relevant scales is an important challenge in ecosystem protection. Indeed, stressors may impact populations at much longer term than the usual timescale of toxicity tests. It is therefore important to study the evolutionary response of a population under chronic stress. We performed a 16-generation study to assess the evolution of two populations of the ubiquitous nematode Caenorhabditis elegans in control conditions or exposed to 1.1 mM of uranium. Several generations were selected to assess growth, reproduction, survival, and dose-responses relationships, through exposure to a range of concentrations (from 0 to 1.2 mM U) with all endpoints measured daily. Our experiment showed an adaptation of individuals to experimental conditions (increase of maximal length and decrease of fecundity) for both populations. We also observed an increase of adverse effects (reduction of growth and fertility) as a function of uranium concentration. We pointed out the emergence of population differentiation for reproduction traits. In contrast, no differentiation was observed on growth traits. Our results confirm the importance of assessing environmental risk related to pollutant through multi-generational studies.
Keywords : Caenorhabditis elegans Multi-generations experiment Evolutionary ecotoxicology Uranium
Document type :
Journal articles
Complete list of metadatas

Cited literature [49 references]  Display  Hide  Download
https://hal-irsn.archives-ouvertes.fr/irsn-00838826
Contributor : Benoit Goussen <>
Submitted on : Sunday, June 1, 2014 - 7:00:14 AM
Last modification on : Thursday, April 19, 2018 - 9:40:01 AM
Long-term archiving on : Monday, September 1, 2014 - 10:35:37 AM

Files

Goussen_et_al_Ecotoxicology.pd...
Files produced by the author(s)

Identifiers

Collections

INERIS | IRSN | TDS-MACS

Citation

Benoit Goussen, Florian Parisot, Rémy Beaudouin, Morgan Dutilleul, Adeline Buisset-Goussen, et al.. Consequences of a multi-generation exposure to uranium on Caenorhabditis elegans life parameters and sensitivity.. Ecotoxicology, Springer Verlag, 2013, 22 (5), pp.869-878. ⟨10.1007/s10646-013-1078-5⟩. ⟨irsn-00838826⟩

Export

BibTeX TEI DC DCterms EndNote

Share

Metrics

Record views

939

Files downloads

538

Contact

support.ccsd.cnrs.fr
hal.support@ccsd.cnrs.fr
Logo CCSD