Application of high-voltage electrical discharges and other alternative technologies for microbial cell lysis and extraction of biocompounds
Résumé
Microbial synthesis offers an interesting alternative to chemical synthesis and a means to complement chemical synthesis to produce molecules of interest. Microbial compounds can either be synthesized intracellularly or extracellularly, and the intracellular ones can be challenging to recover via physical cell disruption methods given the number of variables to be accounted for. Despite this drawback, physical cell disruption technologies continue to prove their effectiveness at recovering high-value compounds resulting from microbial synthesis. High-voltage electrical discharges or HVEDs are very commonly utilized to recover high-value compounds from plant matter and thus valorize biomass which would have otherwise provided little economic value. An increasing body of work has contributed to not only concretizing HVEDs’ utility but also disrupting microbial cells and expanding the technique’s range of applicability.
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